Print
clock clock iconcutlery cutlery iconflag flag iconfolder folder iconinstagram instagram iconpinterest pinterest iconfacebook facebook iconprint print iconsquares squares iconheart heart iconheart solid heart solid icon
This Cajun Chicken Lasagna With Cream Cheese features creamy layers of pasta, spicy Cajun-seasoned chicken, melted cheese, and a rich sauce, making it a standout Cajun Chicken Lasagna Recipe that’s perfect for comfort food lovers.

Creamy Cajun Chicken Lasagna with Cream Cheese – A Comfort Food Favorite


5 Stars 4 Stars 3 Stars 2 Stars 1 Star

No reviews

  • Author: admin
  • Total Time: 1 hour 45 minutes
  • Yield: 12 people 1x

Description

This bold Cajun-inspired lasagna layers smoky sausage, tender chicken, colorful peppers, and a rich cream cheese sauce into one ultra-comforting Southern-style bake. It’s spicy, creamy, and anything but ordinary.


Ingredients

Scale

For the Lasagna

  • 1 (16-ounce) package lasagna noodles, cooked until just tender or use oven-ready noodles
  • 1 pound smoked sausage, sliced and cut into bite-sized pieces
  • 1 pound boneless, skinless chicken breasts, chopped
  • 1 green bell pepper, finely diced
  • 1 red bell pepper, finely diced
  • 1 medium onion, chopped
  • 1 tablespoon Cajun seasoning, divided
  • 3 garlic cloves, minced
  • 2 cups shredded mozzarella cheese
  • 1 cup shredded Monterey Jack cheese
  • ½ cup grated Parmesan cheese

For the Creamy Cajun Sauce

  • 2 sticks unsalted butter
  • 2 packages (8 ounces each) cream cheese, cut into chunks
  • 2 cups heavy cream
  • ⅔ cup grated Parmesan cheese
  • 2 teaspoons garlic powder
  • ½ tablespoon Cajun seasoning
  • Salt and black pepper, to taste


Instructions

  1. Heat a large skillet over medium-high heat. Add the smoked sausage, diced chicken, and half of the Cajun seasoning. Cook until the chicken is fully cooked and no longer pink. Transfer the mixture to a bowl and set aside.
  2. Using the same skillet, sauté the onion, bell peppers, and garlic until soft and fragrant. Remove from heat and stir the cooked meat back into the vegetables. Set aside.
  3. To prepare the sauce, melt the butter in a large saucepan over medium heat. Add the cream cheese and whisk until smooth and fully melted.
  4. Slowly pour in the heavy cream, then add Parmesan cheese, garlic powder, remaining Cajun seasoning, salt, and pepper. Continue whisking until the sauce is creamy and well blended.
  5. Reserve about 1 cup of the sauce. Pour the remaining sauce into the skillet with the meat and vegetables, stirring until everything is evenly coated.
  6. Lightly grease your cooking vessel or baking dish with nonstick spray.
  7. Arrange a layer of lasagna noodles on the bottom. Spread one-third of the meat and sauce mixture over the noodles, then sprinkle with one-third of the mozzarella cheese.
  8. Repeat the layering process two more times, finishing with a final layer of noodles. Pour the reserved sauce over the top, then sprinkle with Monterey Jack and Parmesan cheeses.
  9. Cover and bake at 325°F for 1 hour and 25 minutes, until bubbly and fully heated through.
  10. Let the lasagna rest briefly before slicing and serving.

Notes

  • If you don’t have a multi-cooker, this lasagna works perfectly in a 9×13-inch baking dish. Cover with foil while baking, then uncover during the last 10–15 minutes if you want a golden, bubbly top.
  • Letting the lasagna rest before cutting helps the layers hold together better.
  • Prep Time: 30 minutes
  • Cook Time: 1 hour 15 minutes
  • Category: Main Course

Nutrition

  • Calories: 447 kcal
  • Sugar: 2 g
  • Sodium: 707 mg
  • Fat: 36 g
  • Saturated Fat: 19 g
  • Carbohydrates: 7 g
  • Fiber: 1 g
  • Protein: 24 g
  • Cholesterol: 135 mg